Forge Biologics

Position Overview:

The Scientist II, Process Development - Upstream provides active leadership and execution of the laboratory experiments and protocols for upstream process development efforts. This individual will lead complex experiments, manage junior scientists, and actively contribute to the advancement of AAV manufacturing processes.

Responsibilities:

• Lead and oversee complex experiments for AAV upstream process development, utilizing single-use bioreactors and advanced techniques.
• Provide technical expertise in bioreactor operation, cell culture, and transfection, acting as the Subject Matter Expert (SME).
• Drive process optimization initiatives to enhance AAV yields, quality, and scalability, contributing to project leadership.
• Conduct independent research and lead projects, compiling and contributing experimental data for publications or reports.
• Independently present results and prepare publications or reports, demonstrating strong communication skills.
• Manage and mentor junior team members, reviewing expertimental data and providing guidance and direction.
• Perform individual performance reviews, providing coaching/feedback to ensure employee development.
• Generates protocols/templates that can be utilized by junior team members.
• Develop and revise standard operating procedures (SOPs) and batch records to ensure process consistency.
• Contribute to the development and implementation of innovative process development strategies.
• Oversee day-to-day laboratory activities, including equipment maintenance, supplies management, and cleanliness.
• Support internal process transfer activities from Process Development to GMP.
• Demonstrate a breadth of scientific expertise (knowledge and technique) in laboratory functions that are pertinent to company goals.

Qualifications:

• Bachelor’s Degree in Chemical Engineering, Biomedical Engineering, Biology, or related discipline (or equivalent experience).
• Working knowledge of cell culture techniques utilizing mammalian, insect, or microbial cells.
• Experience in upstream process development and scale up principles.
• Proven ability to operate and troubleshoot bioreactors.
• Experience planning, conducting and reviewing experimental data with minimal oversight.
• Experience analyzing data sets and utilizing the corresponding data to influence decision making.
• Prior experience leading and mentoring junior team members.

Preferred:

• Experience working with viral vectors (AAV, Lentivirus, etc.).
• Experience directly managing junior team members.

Physical Requirements:

This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area.

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned.

Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Life at Forge

We are a team of diverse, driven and passionate people working together to trailblaze a new model for how we make medicines to treat patients with genetic diseases. Our team members use their creativity and talent to invent new solutions, meet new demands, and offer the most effective services in the industry. Forge’s core values lay the foundation for H.O.P.E. It provides us a common purpose that we all understand, work towards and live by.

HARDWORKING - We work hard and smart, making a persistent and determined effort toward success. Working hard, with focus and desire is the key.

OPEN - We strive to be approachable, actively listen and encourage others to contribute and speak up. We positively offer and receive constructive feedback.

PURPOSE DRIVEN - We are passionate about working towards and delivering on our mission to manufacture gene therapies.

ENGAGED - We are fully absorbed by and enthusiastic about our work and take positive action to further Forge’s vision, mission and goals.

We’ve Got You Covered

We take the health and happiness of our employees seriously and are consistently evaluating new ways to make our benefits truly UnFORGEttable.

Health, Dental, and Vision insurance that starts on your first day at Forge, with 90% of premiums covered for team members as well as dependents

Competitive paid time off plan

Annual bonus for all full-time employees

401(K) company match

Fully-stocked kitchen with free food/drinks

12 weeks of paid parental leave - additional discount programs include childcare support & dependent care

Employee Assistance Program

Wellness benefits (financial planning services, mental health counseling, employer paid disability)

Onsite fitness facility

Professional & Personal development resources