Research Specialist - (3284351)
General Summary:
This position will contribute to projects in the laboratories of the Vaccine and Immunotherapy Center on the 5th floor of the MGH East Research Center, 149 13th Street, Charlestown, MA. The research specialist will work with laboratory investigators under the direct supervision of the VIC Director to carry out assigned functions related to research projects and computational infrastructure. Primary research activities will include statistical and computational analysis of high-dimensional data sets derived from flow and mass cytometry (CyTOF) and high-dimensional imaging technologies, and may include bench experiments as assigned. This position will also have particular responsibilities related to electronic data management for large data sets to ensure data accessibility for analysis while remaining in compliance with institutional and federal requirements regarding patient privacy and data integrity.
Principal Duties and Responsibilities:
A highly motivated individual researcher with experience in mathematics and/or computational biology and familiarity with laboratory research will contribute to the analysis of data derived from complex biological samples. The candidate will be expected to develop and/or demonstrate proficiency in high-parameter analysis for both cytometry and nucleic acid analyses. There is additional opportunity to refine current approaches and develop novel methods for data analysis.
Applicant should have the fundamental skills necessary to plan and execute data analysis strategies in an independent manner, including interpretation and troubleshooting. Work will comprise the implementation and/or refinement of existing analysis pipelines in Python and R, as well as the development of additional ones. The position will require analysis of diverse sets of information and data to form a cohesive and thoughtful hypothesis and contributing to the design of experiments to drive the project forward. The applicant should be able to work well with a team of investigators with diverse expertise to develop and implement novel analysis pipelines. Also essential is the preparation of presentations, reports, and manuscripts for publication. The position may also co-develop funding proposals with the VIC Director or individual laboratory heads.
Excellent record keeping skills are an absolute requirement. Detailed accounting of planning, execution, and analysis of experiments is mandatory. This position will entail an integral role in collaborative research projects; therefore excellent communication skills, detailed record keeping, protocol standardization, and attention to organization are essential elements of the role.
Skills and Abilities:
1. Basic competency with Microsoft Office Suite: MS Word, MS Excel, MS Powerpoint.
2. Highly organized and methodical.
3. Ability to follow detailed oral and written instructions.
4. Effective written and oral communication skills.
5. Able to work constructively in team settings.
6. Competency in applied mathematics (linear algebra, discrete math, and familiarity of applied mathematics for analysis of biological datasets, including self-organizing maps, k-means clustering, and neural networks) and statistics and use of associated computational tools such as Prism, MATLAB, R, and Python.
7. Experience with digital image analysis
8. Experience with writing scientific manuscripts and/or grants.
9. Familiarity with the basic concepts of immunology will be a plus.
Supervisory Responsibility:
May supervise junior computational staff and/or student interns (up to 3-4 FTEs). May also co-supervise or train technicians or students from various lab teams whose projects have a significant component of computational data analysis.
Masters degree or higher in mathematics, statistics, computer science, or similar discipline required.
Must possess at least 7 years of cumulative relevant research experience.
EEO Statement Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.
: MA-Charlestown-MGH 13th Street
:
MGH 13th Street
149 13th Street
Charlestown 02129
: Technician/Technologist/Scientist
: Massachusetts General Hospital(MGH)
: Full-time
Standard Hours: 40
: Day Job
: Regular
Recruiting Department: MGH Infectious Disease
: Apr 2, 2024
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