Henry Ford Health

Post-Doctoral Fellow – Biomarkers in Glioblastoma

Position Summary

We are seeking a highly motivated Post-Doctoral Fellow to join our translational oncology team focused on biomarker discovery and validation in glioblastoma. The successful candidate will work at the intersection of computational biology, imaging science, and clinical research, applying advanced methods in genomics and radiomics to large patient datasets. This role also involves meaningful engagement with patients, physicians, and research staff to ensure high-quality collection and processing of biospecimens for downstream analyses. You will join a growing team of physicians and scientists at Henry Ford Health and Michigan State University Health Sciences as we build our start-of-the-art joint research center in Detroit, Michigan.

Key Responsibilities

• Conduct large-scale analyses of genomics, transcriptomics, and radiomics datasets to identify biomarkers of prognosis, treatment response, and resistance in glioblastoma.
• Develop and apply computational pipelines, machine learning, and integrative modeling approaches to multi-omics and imaging data.
• Collaborate with physicians, research coordinators, and laboratory staff to facilitate patient consent, biospecimen collection, and standardized sample processing.
• Work closely with a multidisciplinary team of oncologists, radiologists, data scientists, and laboratory investigators to design and execute translational studies.
• Prepare manuscripts, presentations, and grant applications to disseminate findings and support funding efforts.
• Mentor junior trainees and contribute to a collaborative, team-based research environment.

Qualifications

• PhD in Computational Biology, Bioinformatics, Biomedical Engineering, Cancer Biology, or a related discipline.
• Strong background in analysis of large-scale genomic and/or imaging datasets; experience with radiomics is highly desirable.
• Proficiency in relevant programming and statistical tools (e.g., Python, R, MATLAB, machine learning frameworks).
• Familiarity with next-generation sequencing data, multi-omics integration, and biomarker discovery pipelines.
• Excellent communication and interpersonal skills, with the ability to interface effectively with patients, clinicians, and scientists.
• Prior experience in neuro-oncology, cancer genomics, or imaging research is a plus but not required.

Opportunities

This fellowship provides unique training in cutting-edge biomarker discovery within a highly collaborative environment at the interface of clinical and translational science. Fellows will have access to advanced imaging platforms, state-of-the-art sequencing technologies, and well-curated longitudinal datasets from glioblastoma patients. The position offers strong mentorship and opportunities for career development toward independent research leadership.

For more information, please contact Eric A. Mellon, MD, PhD at emellon1@hfhs.org.

GENERAL SUMMARY:

Under the direction of a senior investigator, designs, executes, analyzes, and interprets various laboratory experiments with a focus on current scientific questions, as identified by the senior scientists.

EDUCATION REQUIRED:

• Ph.D. or equivalent doctoral degree in a field related to the department's research.

EXPERIENCE REQUIRED:

• Experience in basic science or clinical research is required.
• This should be demonstrated by abstracts, presentations at meetings, and publications in peer-reviewed journals that are references in databases such PubMed.
• Alternatively, the applicant must have submitted his/her thesis work for publication.
• A proven working knowledge of various research methodologies and biostatistics required.

Additional Information

• Organization: Henry Ford Medical Group
• Department: Radiation Oncology-Prof
• Shift: Day Job
• Union Code: Not Applicable

Additional Details

This posting represents the major duties, responsibilities, and authorities of this job, and is not intended to be a complete list of all tasks and functions. It should be understood, therefore, that incumbents may be asked to perform job-related duties beyond those explicitly described above.

Overview

Henry Ford Health partners with millions of people on their health journey, across Michigan and around the world. We offer a full continuum of services – from primary and preventative care to complex and specialty care, health insurance, a full suite of home health offerings, virtual care, pharmacy, eye care and other health care retail. With former Ascension southeast Michigan and Flint region locations now part of our team, Henry Ford’s care is available in 13 hospitals and hundreds of ambulatory care locations. Based in Detroit, Henry Ford is one of the nation’s most respected academic medical centers and is leading the Future of Health: Detroit, a $3 billion investment anchored by a reimagined Henry Ford academic healthcare campus. Learn more at henryford.com/careers.

Benefits

The health and overall well-being of our team members is our priority. That’s why we offer support in the various components of our team’s well-being: physical, emotional, social, financial and spiritual. Our Total Rewards program includes competitive health plan options, with three consumer-driven health plans (CDHPs), a PPO plan and an HMO plan. Our team members enjoy a number of additional benefits, ranging from dental and eye care coverage to tuition assistance, family forming benefits, discounts to dozens of businesses and more. Employees classified as contingent status are not eligible for benefits.

Equal Employment Opportunity/Affirmative Action Employer

Equal Employment Opportunity / Affirmative Action Employer Henry Ford Health is

committed to the hiring, advancement and fair treatment of all individuals without regard to

race, color, creed, religion, age, sex, national origin, disability, veteran status, size, height,

weight, marital status, family status, gender identity, sexual orientation, and genetic information,

or any other protected status in accordance with applicable federal and state laws.