Repligen

Overview

We are seeking a Senior Scientist, Downstream Purification to join our growing custom affinity resin development team. The successful candidate will play a key role in testing affinity resins derived from Avitide's proprietary affinity ligand discovery platform for purificaion of biopharmaceutical products. This is an opportunity to work on cutting-edge projects in a collaborative environment.

We are an innovative life sciences company focused on developing and commercializing high-value bioprocessing products, technologies, and solutions critical in the production of biologic drugs.

You will be part of a cross functional team of highly motivated and collaborative colleagues that perform downstream process development to understand the performance of Repligen's custom affinity resins and communicating results with external partners. This role will be based in Lebanon, NH and will report to the Director of Downstream Development.

Responsibilities

The Senior Scientist, Downstream Purification will be responsible for:

• Rapid development of affinity chromatography purification methods for various biopharmaceuticals, ensuring scalability, and efficiency, with an emphasis on high throughput screening techniques.
• Collaboration: Work collaboratively with cross-functional teams including Ligand Discovery, Analytical Sciences, Resin Manufacturing to ensure project success.
• Troubleshooting: Investigate and resolve technical issues related to affinity resin performance and characterization. A general working knowledge of cutting edge biotherapeutic molecules is a bonus.
• Training and Mentorship: Provide training and mentorship to junior scientists and technicians within the downstream process development team.

Qualifications

• Education: PhD or Master’s degree in Chemical Engineering, Biochemistry, Biotechnology, or related field.
• Experience: Minimum of 3 years (PhD) or 5 years (Master’s) or 8 years (Bachelor's) of experience in downstream process development within the biopharmaceutical industry.
• Technical Skills: Proficiency in chromatography, filtration, ultrafiltration/diafiltration (UF/DF), and other downstream purification techniques.
• Communication: Excellent verbal and written communication skills, with the ability to effectively present technical information and collaborate across disciplines.
• Problem-Solving: Proven track record in troubleshooting and solving technical challenges related to downstream processes.

What Repligen Offers

Repligen offers you a competitive remuneration package, including a yearly bonus, non-contributory pension, generous PTO, partial compensation on your personal health insurance and flexible working hours. But most importantly Repligen offers you a stimulating, collaborative environment with steep learning curves and the opportunity to contribute to the healthcare of patients worldwide. All of this with an international team in Waltham, MA.