Associate Principal Scientist, Medicinal/Discovery Chemistry

Merck & Co.

Job Description

At our company, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough. Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility, and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At our Research Labs, you’ll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

Our company is currently seeking an experienced medicinal chemist, collaborator, and mentor to join the Discovery Chemistry Department at our West Point, PA site. The successful candidate will have responsibility for contributing to multidisciplinary, highly collaborative discovery teams within our portfolio and for scientific talent development. 

Specific responsibilities for this role will include the following:

  • Design, synthesize, and characterize high impact molecules for programs at all stages of discovery.
  • Lead by example in the laboratory, driving program and chemistry strategy execution.
  • Develop and utilize innovative synthetic chemistry strategies to solve complex medicinal chemistry problems.
  • Analyze diverse data sets to build structure-activity relationships and employ in silico tools in the iterative design of target molecules. 
  • Actively participate in the recruitment, training, and development of scientific staff
  • Collaborate across departments to identify and validate new targets, which may include collaborative engagement with the external scientific community and leadership of early drug discovery projects.
  • Enhance external scientific presence through authoring significant scientific publications and presentations.

To accomplish these goals, the successful candidate should have the following minimum qualifications, and required skills and experience:

Minimum qualifications:

  • Ph.D. in chemistry with a minimum of 4 years of industry experience in drug discovery or,
  • M.S. in chemistry with a minimum of 8 years of industry experience in drug discovery or,
  • B.S. in chemistry with a minimum of 12 years of industry experience in drug discovery

Required skills and experience:

  • Experience in synthesis, purification, and analytical characterization of drug candidate molecules via methods such as HPLC, MS, NMR, and biophysical methods
  • Experience in therapeutic design, strategy execution, and interpretation of biological data
  • Track record of solving complex chemistry problems
  • Awareness of key scientific and technology advances in the external community
  • Demonstrated leadership in the training and mentoring of team members in synthesis and drug discovery
  • Effective communication, collaboration, and leadership skills in a team environment

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

Search Firm Representatives Please Read Carefully 

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

N/A

Read Full Description
Confirmed 6 hours ago. Posted 13 days ago.

Discover Similar Jobs

Suggested Articles