Research Scientist - Protein Purification

Oxford Nanopore

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe.

Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.

Oxford Nanopore’s sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere!

We are looking for a highly motivated individual to join the Protein Purification Team as a Research Scientist with a primary responsibility to express and purify a range of recombinant protein components for our disruptive nanopore sequencing technology. This will be carried out by following established protocols and establishing new methods where required.

As one of the key components of our technology, we continuously strive to improve and upgrade our protein components whilst simultaneously developing new methods of expression and purification. Working within a focused team in the research department, this predominantly lab-based role will involve the purification and characterisation of a variety of enzyme motor proteins, nanopores and other novel targets.

The successful candidate will be working alongside other research scientists to express and purify different proteins for electrophysiological characterisation and bulk kinetic assays. Expression and purification is carried out via traditional E.coli expression and high throughput expression utilising liquid handling robots.

What we're looking for...

Applications from scientists with backgrounds in a relevant subject area, ideally with previous industrial experience, these include:

  • Biochemistry
  • Biology
  • Molecular Biology
  • Chemical Biology

You will have:

  • A good working knowledge of recombinant protein expression, purification and subsequent characterisation
  • Hands on experience in working with AKTA systems, particularly in relation to nucleic acid handling proteins and membrane proteins.
  • Experience of liquid handing robots is desired but not essential
  • We are looking for applicants who can adapt quickly to new challenges and enjoy working with an agile approach to research!

You'll be used to working meticulously and to a high standard, as well as being able to perform well under pressure. You'll be used to meeting deadlines in a complex and fast paced environment.

Working within a dynamic, multidisciplinary team, successful candidates will be able to communicate results to other team members successfully. Full training will be given.

We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.

If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today!

Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

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Oxford Nanopore’s goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments.

Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.

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Confirmed 10 hours ago. Posted 30+ days ago.

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