The Center for Applied Bioinformatics at St. Jude Children's Research Hospital is looking for a highly motivated and creative senior bioinformatics scientist to develop and apply innovative analytical approaches to establish the molecular classifier of pediatric cancers. The scientist will have the opportunity to explore newly available methods, pipeline development could result in high-profile publications, as long as it aligns with our ultimate goal: “Finding cures. Saving children”.

The Center provides a highly interactive environment with collaborative opportunities within the centers including transcriptomics group, genomics group, and genetics group, and across basic and clinical departments, access to high-performance computing clusters, cloud computing environment, novel sequencing platforms such as long reads sequencing technologies, single-cell sequencing at both DNA and RNA level and spatial transcriptomics, innovative visualization tools, highly automated analytical pipelines powered by GPU technology and mentorship from scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The members of this Center could work on broad areas of bioinformatics and gain valuable experiences. The members of this Center also have the opportunity to publish high-profile papers with prominent authorship and file patents for novel biomarker discoveries or novel methods for clinical diagnosis or disease treatment. 

The successful candidate is expected to have strong programming skills in Bash, Python, and R, strong machine learning skills for classification, and experience in developing computational methods and optimizing analysis workflows for high-throughput next-generation sequence data (such as transcriptome sequencing, whole-genome sequencing and so on) under Linux/Unix environment. 

Responsibilities 

• Specific responsibilities involve the build and refinement of the approach and machine learning models for classification/subtyping of pediatric cancers. 
• Other responsibilities may involve NGS data quality control, integrative analyses, data visualization, developing and evaluating analytic tools 
• Excellent communication skills are essential 

Minimum Education and/or Training:

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Master's degree or PhD preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
• Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience.
• Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.

Other Information

St. Jude is an Equal Opportunity Employer

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