PostDoctoral Research Scientist in The Institute for Cancer Genetics

Columbia University

Postdoctoral positions are available to study mechanisms of epigenetic inheritance and cancer epigenetics at Columbia University Irving Medical Center. Candidates with a strong background in molecular biology, cancer biology, protein purification, and structural biology are strongly encouraged to apply. Detailed information about our laboratory and research projects can be found online: https://zgzhanglab-columbia.com

Interested candidates should email their CV and the names of three references to zz2401@cumc.columbia.edu

SELECTED PUBLICATIONS:

1. Xu X, Duan S, Hua X, Li Z, He R, and Zhang Z. Stable inheritance of H3.3-containing nucleosomes during mitotic cell divisions (2022). Nature Communications, 13: 2514.

2. Mo Y, Duan S, Zhang X, Hua X, Zhou H, Wei HJ, Watanabe J, McQuillan N, Su Z, Gu W, Wu CC, Vakoc CR, Hashizume R, Chang K, and Zhang Z. Epigenome programing by H3.3K27M mutation creates a dependence of pediatric glioma on SMARCA4 (2022). Cancer Discovery, 12: 2906–2929.

3. Yu C, Gan H, Serra-Cardona A, Zhang L, Gan S, Sharma S, Johansson E, Chabes A, Xu RM, and Zhang Z. A mechanism for preventing asymmetric histone segregation onto replicating DNA strands (2018). Science, 361: 1386­­­–1389.

4. Zhang L, Serra-Cardona A, Zhou H, Wang M, Yang N, Zhang Z*, and Xu R*. Multisite substrate recognition in Asf1-dependent acetylation of histone H3K56 by Rtt109 (2018). Cell, 174(4): 818–830. 

5. Fang* D, Gan* H, Lee* J, Han* J, Wang* Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, Bridge JA, Thibodeau SN, Ordog T, Chen Y, van Wijnen AJ, Oliveira AM, Xu R, Westendorf JJ, and Zhang Z. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas (2016). Science, 352: 1344­–1348.

We seek candidates who are recent Ph.D. graduates and have explicit interests in cancer research. 

Salary is commensurate on years of postdoctoral experience.

Interested candidates should email their CV and the names of three references to zz2401@cumc.columbia.edu

Columbia University is an Equal Opportunity Employer / Disability / Veteran

Pay Transparency Disclosure

The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

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