The Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) core lab consists of the Analytical Chemistry and Pharmacology Core (ACPC) lab and the Translational Oncology and Nanoparticle Drug Development Initiative (TONDDI) lab. The ATPAC core lab uses analytical chemistry and pharmacologic infrastructure to support the translational development of drugs, anticancer agents, carrier-mediated agents and biologics. The lab provides expertise in translational drug development, analytical chemistry, pharmacology [pharmacokinetic (PK) and pharmacodynamic (PD); efficacy and toxicity], and biomarker studies.The Research Associate position includes acting as the lab manager and as an analytical chemist the UNC Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Lab with guidance from the Director Dr. William Zamboni. As related to the lab manager requirements, s/he will be expected to contribute consistent process improvement to all systems in the laboratory including communicating and managing changes to these lab processes. The position focuses on working directly with collaborators, managing laboratory operations, performing and training users for LC-MS/MS and ICP-MS analyses. The Research Associate will support grant, contract and publication submissions by contributing budgets and writing key sections. This position will also be responsible for generating, submitting, and documenting costs, invoices, and payments for internal and external UNC projects. As related to the analytical chemist requirements, this position will develop and validate analytical assays and analyze samples in blood/plasma, tissue, and tumors samples as part of preclinical and clinical pharmacology studies. The position holder will work independently to provide support to collaborator-sponsored projects in the lab; program, operate, and troubleshoot equipment and related IT systems; optimize and perform analytical assays; and serve as a backup resource for phenotypic screening assays. This position will also be expected to present work locally and at scientific conferences.
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