Zoetis

FORMULATION SCIENTIST

We are seeking a formulation scientist at the Principal Scientist or Senior Principal Scientist level to support development of new veterinary drug products and reformulation of existing products at our R&D headquarters in Kalamazoo, Michigan, with an emphasis on liquid formulation development. The formulation scientist will be responsible for characterization of candidate molecules, designing early enabling formulations, conducting preformulation research, developing formulations and manufacturing processes and scale-up and transfer into production facilities. This is an exciting opportunity where the scientist will have full ownership on formulation development, scale-up and technical documentation. The scientist will also work with global manufacturing colleagues for technology transfer and production of registration stability batches. The scientist will be expected to support interdisciplinary teams of colleagues from research (biologist, medicinal chemist, pharmacologist), clinical development, safety, regulatory and marketing. On occasion, the scientist will be expected to lead pharmaceutical science teams which bring forward the active molecule, drug product, analytical methods and drug supplies for drug candidates from early discovery stage to commercialization. The focus of this formulation position is liquid formulation development (sterile injectable, solution, suspension). The scientist will also have the opportunity to work on various additional dosage forms including oral (tablets, medicated feed additives) and topical. The scientist will have the opportunity to work on various innovative projects to tailor dosage forms based on specific needs of different animal species.

RESPONSIBILITIES

• Formulation design, development and scale-up of the manufacturing process.
• Support discovery team with enabling formulations.
• Research and development of novel drug delivery systems internally and/or through external partners.
• Conduct formulation research in the laboratory and provide pharmaceutical science leadership when appropriate.
• Author regulatory documents for filing and commercial launch.

EDUCATION AND EXPERIENCE

• PhD in Pharmacy, Pharmaceutics, Chemical Engineering or related field with at least 5 years of experience in the pharmaceutical industry.
• Experience in conducting preformulation and formulation development studies.
• Experience with liquid dosage forms (sterile injectable, solution, suspension).
• Extensive knowledge of drug degradation pathways and stabilization techniques.
• Experience with international teams, CROs/CMOs.
• Knowledge on Design of Experimentation and Quality by Design aspects for formulation development.
• Effective communication and leadership skills.

OTHER DESIRABLE ATTRIBUTES (but not necessary)

• Experience with other types of formulation development (e.g. solids, feed additives, etc.).
• Familiarity of the Animal Health industry with experience of working with Marketing/Commercial colleagues.
• Familiarity with GMP, VICH, Pharmacopeias, Technical and Regulatory requirements in relation to animal health product development and manufacturing.
• Familiarity in scale-up and technology transfer to pilot/commercial scale.
• Experience with writing CMC technical sections.
• Understanding of packaging considerations for commercial products and primary pack screening and selection activities

Full time

Regular

Colleague

Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of “@zoetis.com”. In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.