AMRI Global

Senior Research Scientist; Protein Expression & Purification in Buffalo, NY

Build your future at Curia, where our work has the power to save lives.

The Senior Research Scientist, Protein Expression and Purification, is an integral part of the Curia team, contributing to our success by demonstrating expertise in both the theoretical and practical aspects of protein purification and characterization. Principal responsibilities are experimental design, conduct production & analysis experiments, maintain detailed records and generate standard operating procedures. Major components of the scientist's performance rating will be based on productivity, teamwork, analytical competence and experimental decision making.

Curia is a global contract development and manufacturing organization (CDMO) with over 30 years of experience partnering with pharmaceutical and biotech companies to provide life-saving treatments to patients. At Curia, we are on a mission to advance our customers’ therapies from curiosity to cure and ultimately to improve patients’ lives.

We proudly offer

• Generous benefit options (eligible first day of employment)
• Paid training, vacation and holidays (vacation accrual begins on first day of employment)
• Career advancement opportunities
• Education reimbursement
• 401K program with matching contributions
• Learning platform
• And more!
• Conduct protein purification with FPLC including affinity, ion exchange, HIC, etc.
• Conduct protein purification from E. coli, mammalian and/or insect cells.
• Run protein characterization including: HPLC, SDS-PAGE, native PAGE, western blot, DLS, capillary electrophoresis, and endotoxin assay.
• Be responsible for cell culture maintenance and transfections including: CHO, HEK 293, Sf9, and Sf21.
• Run molecular cloning including: PCR, DNA digestion, ligation, and mutagenesis.
• Present data (written and/or oral) to clients as necessary.
• Bachelor’s degree in Biology or Biochemistry with a minimum of 5-8 years’ related experience, or, a Master’s degree in Biology or Biochemistry with a minimum of 3-6 years’ related experience, or, a PhD with 0-3 years’ related experience
• Extensive experience with cell culture and recombinant protein purification
• Prior experience with protein purification system such as AKTA, NGC, or similar is desired
• Skill of planning and organization of multiple projects simultaneously
• Ability of scientific data presentation and client communication
• Prior experience with molecular cloning and protein analysis is preferred
• Prior experience of purification of challenging proteins and troubleshooting skills are preferred
• Prior crystallization and cryo-EM experience is an asset

Responsibilities

• Conduct protein purification with FPLC including affinity, ion exchange, HIC, etc.
• Conduct protein purification from E. coli, mammalian and/or insect cells.
• Run protein characterization including: HPLC, SDS-PAGE, native PAGE, western blot, DLS, capillary electrophoresis, and endotoxin assay.
• Be responsible for cell culture maintenance and transfections including: CHO, HEK 293, Sf9, and Sf21.
• Run molecular cloning including: PCR, DNA digestion, ligation, and mutagenesis.
• Present data (written and/or oral) to clients as necessary.

Qualifications

• Bachelor’s degree in Biology or Biochemistry with a minimum of 5-8 years’ related experience, or, a Master’s degree in Biology or Biochemistry with a minimum of 3-6 years’ related experience, or, a PhD with 0-3 years’ related experience
• Extensive experience with cell culture and recombinant protein purification
• Prior experience with protein purification system such as AKTA, NGC, or similar is desired
• Skill of planning and organization of multiple projects simultaneously
• Ability of scientific data presentation and client communication

Preferred

• Prior experience with molecular cloning and protein analysis is preferred
• Prior experience of purification of challenging proteins and troubleshooting skills are preferred
• Prior crystallization and cryo-EM experience is an asset

Other Qualifications

• Must pass a background check
• Must pass a drug screen
• May be required to pass Occupational Health Screening

Pay Range: $79,000/yr.

Education, experience, location and tenure may be considered along with internal equity when job offers are extended.

We do not accept unsolicited assistance from any headhunters or recruitment firms for any of our job openings. All resumes or profiles submitted by search firms to any employee at Curia, in any form without a valid, signed search agreement by an authorized signatory in place for the specific position, approved by Talent Acquisition, will be deemed the sole property of Curia. No fee will be paid in the event the candidate is hired by Curia because of the unsolicited referral.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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