University of Colorado

Job Summary

Job Summary

The Park Lab invites applications for a Temporary Researcher to conduct basic molecular and biochemical experiments, to understand mechanisms of proteasome assembly and regulation.

CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.

Who We Are

Who We Are

Park's Lab at the University of Colorado Boulder

We study the proteasome, a central mediator of protein breakdown. Functions and mechanisms of the proteasome are extremely conserved in eukaryotes, allowing our research findings to be broadly applicable to many organismal contexts, from a simple model as budding yeasts to a more complex, human stem cells, for example. A major research question in Park lab is to understand how the proteasome, a complex molecular machine, assembles via multiple dedicated chaperone proteins. How do these chaperones enable proteasome assembly accurately and efficiently? How do they 'know' faulty vs. correct complexes, and act on them properly? Cell's ability to supply the proteasome is essential to life, and survival through many stressed conditions, including "nutritional stresses". In particular, cancer cells frequently encounter nutritional stresses, and many of them alter expressions of proteasome assembly chaperones. For more detailed description of our current projects, please see Research section of our website.

What Your Key Responsibilities Will Be

What Your Key Responsibilities Will Be

• Major responsibilities include 1) performing various types of PCRs and microscopic dissection to construct yeast strains and plasmids, and 2) analyzing them via confocal microscopy, gel-based and structural strategies.

What We Can Offer

What We Can Offer

The hiring rate for this position is $18.00 per hour.

Benefits

Benefits

Temporary positions at the University of Colorado are not benefits-eligible, however, all positions are eligible for paid sick leave.

Be Statements

Be Statements

Be ambitious. Be pioneering. Be Boulder.

What We Require

What We Require

• A combination of education and/or relevant experience that demonstrates the ability to successfully perform the duties of the position.

Special Instructions

Special Instructions

To apply, please submit the following materials:

1. Resume or CV
2. Cover letter addressed to the Search Committee briefly describing your qualifications, professional goals, and specific interest in this position.

During the application process you will need to enter contact information for a reference. We will request a letter of recommendation and additional materials, if needed, as the search progresses.

Please apply by October 17, 2025 for full consideration. The position will remain posted until filled.

Note: Application materials will not be accepted via email. For consideration, applications must be submitted through CU Boulder Jobs.