Johnson and Johnson

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Nonclinical Safety

Job Category:

Scientific/Technology

All Job Posting Locations:

Beerse, Antwerp, Belgium

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, Occupational Toxicology & Product Quality to be located in Beerse, Belgium.

Please note that this role is available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s):

United States - Requisition Number: R-018339

Beerse, Belgium - Requisition Number: R-021941

Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.

Purpose:

The Principal Scientist, Occupational Toxicology & Product Quality will play a vital role in supporting the completion of comprehensive human health risk assessments for active pharmaceutical ingredients (APIs) throughout the drug development process. In this position, the qualified candidate will collaborate closely with toxicologists and cross-functional teams to ensure compliance with evolving regulatory requirements, thereby helping to ensure worker safety and product quality. Key responsibilities will include conducting and communicating risk assessments for new molecular entities (NMEs) and established products (EPs), as well as contributing to the advancement of innovative methodologies for health-based assessments. If you possess a solid background in toxicology and are passionate about worker safety and product quality, we encourage you to apply and become part of our dedicated and innovative team at Johnson & Johnson!

You will be responsible for:

• Apply toxicological knowledge to establish health-based permitted daily exposure levels (PDEs) and occupational exposure limits (OELs) for APIs throughout their synthesis stages.
• Provide training and hazard information on occupational health, including safety data sheet reviews and reproductive hazard assessments.
• Monitor ongoing toxicology studies to ensure adherence to protocols and regulations.
• Leverage occupational toxicology knowledge to provide scientific support for small molecules, antibody drug conjugates (ADC) and other modalities.
• Participate in the Pharma Occupational Toxicology Advisory Committee as part of the assessment peer-review process.
• Collaborate with internal and external teams to enhance risk assessment efficacy and adapt to emerging regulations.
• Maintain up-to-date knowledge of global worker safety regulations and participate in activities to influence regulatory decisions.
• Engage in ongoing training opportunities while supporting cross-training initiatives within the department.

Qualifications / Requirements:

Education:

• Minimum of Bachelor’s degree is required
• Master’s degree or PhD in Toxicology, Pharmacology or related area is highly preferred

Required:

• Minimum 6-8 years of experience in the pharmaceutical industry/academic setting (i.e. preclinical safety assessment, risk assessment, public health, etc.)
• Experience working in a regulatory environment
• Proven history of integrating toxicology and clinical data into clear risk assessments
• Highly motivated, innovative, and team-oriented mindset
• Excellent written, visual, and oral communication skills
• Ability to work in a fast-paced, global environment and adapt quickly to changing company needs while collaborating across functions.
• Travel up to 10%, defined by business need

Preferred:

DABT certification