University of Minnesota

About the Job

The successful candidate will be designated as an Essential Employee. Essential Employees are expected

to report to campus during a University State of Emergency (reduced operations or campus closure)

unless specifically directed by the Department not to report or if directed by civil emergency or medical

authorities not to report for health and safety reasons. As an Essential Employee, you must report to

campus even if the closure is less than 3 days.

Responsibilities:

50% - Conduct blood and marrow transplant and anti-tumor experiments with mouse and human T cellsin support of clinical applications. A range of activities will be expected:

• Perform primary cell isolation and enrichment under supervision.
• Conduct tissue collection in a team-centered approach.
• Flow cytometric staining and processing. Analysis will be done be the PI, experienced lab

member, or by the incumbent under direct supervision.

• Biochemical analyses to include DNA, RNA, and protein (immunoblot) evaluation

Candidate will be expected to:

• Undertake standard laboratory analyses independently, carefully following detailed laboratory protocols.
• Perform experiments, under moderate supervision, consisting of either multiple timepoints or a variety of experimental variables.
• Keep accurate records of experimental outlines and results.

20% - Cell culture, team science, and reagent preparation. These duties will include:

• Perform basic cell culturing of standard cell lines.
• Undertake cloning and preparation of common bacterial and lentiviral vectors, under

supervision.

• Maintain common stocks of media, buffers and commonly used reagents

Candidate will be expected to:

• Work and communicate with others in a team-centered approach.
• Be flexible in their thinking and timing to more than one task on the same day.
• Practice a thorough approach to scientific execution and maintain a high internal standard of quality control.
• Maintain exquisite quality control of stock reagents

20% - Data review and overall lab management

• Diligently document experiments in lab notebooks.
• Prepare summary reports of experimental results to share with supervisor.
• Ensure lab maintenance (ordering supplies, checking inventory), including completion of

regulatory paperwork as required (OSHA, IACUC, radiation safety).

• With direction from the PI, will implement and revise an organizational framework for the lab.

This will include, but not be limited to, maintaining a spreadsheet of lab duties, ensuring proper maintenance of lab notebooks, and documenting freezer stocks and reagent inventory.

• Delegate shared lab duties to other members of team
• Other projects as assigned by supervisor.

Candidate will be evaluated based upon:

• Ability to track lab usage of common reagents and provide replacements in a timely fashion.
• Timeliness in completing regulatory paperwork as well as open communication with regulatory agencies inside and outside the university.
• Systematic organization of the lab and proper delegation of tasks to all lab members

10% - Act as a resource for medical students and undergraduates. Help on-board new lab members

• Serve as a front-line resource for day-to-day general, lab-related questions (e.g., where is the media kept?).
• General onboarding of new lab members, including assignment of proper online manuals and modules
• Training of new technicians in specific areas and as directed by the PI
• Generally ensure that proper techniques and standardized methods are being followed across laboratory personnel.

Candidate is expected to demonstrate:

• Open communication with multiple members of the laboratory
• Working knowledge of protocols and techniques that are common to the laboratory

Qualifications

Qualifications

All required qualifications must be documented on application materials

Required Qualifications:

• BA/BS in a scientific or health related field and at least 2 years of research experience OR a combination of education and experience in research to equal at least 6 years
• Experience working within a basic or translational science research setting and documented ability to perform experiments in a research capacity with more than one variable or time point
• General exposure to molecular biology and particular experience in cell culture, including the practice of aseptic technique
• Experience reporting effectively on the progress and direction of individual projects using

written and verbal English, to include proper grammar usage and accurate spelling

• Demonstrated data management skills, including data collection, data entry and quality control
• Computer proficiency and ability to navigate basic software applications (Microsoft Word, Excel, Powerpoint) and online data storage (shared drives, google sheets, etc.)
• Ability to work both independently, with moderate supervision, and as part of a team
• Capacity to adopt flexible work hours, including occasional evenings and weekends

Preferred Qualifications:

• Previous experience working with and handling mice in a research setting. Candidate would be expected to pick up, manipulate, and restrain mice; administer therapeutics (e.g. via intraperitoneal injection); and collect blood samples from living mice
• A working knowledge of immunology and murine models of disease.
• Previous experience working with models of in vivo tumor responses, bone marrow

transplantation, or graft-versus-host disease

• Ability and desire to contribute to laboratory meetings and attend and participate in journal

clubs

• Experience with flow cytometry to include staining of cells and running of samples
• Familiarity in ordering lab supplies and keeping a laboratory well-provisioned
• Excellent written, verbal, and interpersonal skills

About the Department

Peds BMT Byersdorfer Lab

This position is located in the Department of Pediatrics, Division of Blood and Marrow Transplantation.

Specifically, the applicant will be working in a laboratory that employs cellular engineering to deliver

therapies for both blood and marrow transplantation and for cancer patients suffering from relapsed or

refractory disease. The lab uses animal models and precise genetic engineering to modulate the

therapeutic potential of various subsets of immune cells.

Pay and Benefits

Pay Range: $57,000 - $65,000/annually, depending on education/qualifications/experience

Time Appointment Category: 100% Appointment (If job description above does not specify appointment or expected weekly hours, assume a 100% appointment.)

Position Type: Civil-Service & Non-Faculty Labor Represented Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

How To Apply

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

Diversity

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Employment Requirements

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

About the U of M

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America’s Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).

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