Amgen

Career Category

Information Systems

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

The Amgen Capability Center in Lisbon, Portugal (ACCP) will be home to over 300 multi-national and multi-cultural employees, representing a broad range of cross functional capabilities, including Commercial, General and Administrative, Research and Development and more. The ACCP will offer rich career growth and development opportunities, regional and global exposure, and the opportunity to LIVE, WIN and THRIVE in one of Europe’s most attractive cities.

Our ACCP Office is located at Maleo – Sete Rios, Av. José Malhoa 19, 1070-040 Lisbon, in the vibrant city center of Lisbon.

If you feel like you’re part of something bigger, it’s because you are. At Amgen our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that read over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.

Sr Associate Artificial Intelligence Security Engineer

LIVE

What you will do

Amgen is seeking an IS Security Engineer who will report to the Senior Manager Global AI Security leader in our Cybersecurity and Digital Trust (CDT) organization and will be based in Lisbon Portugal, at Amgen’s Capability Center. At Amgen, our mission is simple: to serve patients. Our Capability Center provides essential services that enable us to better pursue this mission. This state-of-the art center serves as a base for finance, information systems, and human resources professionals to make a meaningful impact at one of the world’s leading biotechnology companies.

This position will join our cybersecurity team in securing the artificial intelligence and machine learning (AI/ML) systems that power innovation in Amgen. This role is essential in protecting sensitive biomedical data, safeguarding research models, and ensuring the trustworthiness of AI tools used in drug discovery, clinical development, and digital health.

The Security Engineer will work closely with cybersecurity architects, data scientists, bioinformaticians, and DevOps engineers to ensure our AI systems are designed, deployed, and maintained securely across cloud and on-prem environments. This is a senior technical role with influence across engineering, data science, and cybersecurity domains, will play a critical role in securing sensitive biomedical data, protecting proprietary models, and embedding resilience and compliance into our AI systems used in drug discovery, genomics, and digital health.

WIN

What we expect of you

Job Responsibilities:

• Design and implement secure-by-design AI/ML environments across cloud and on-premise platforms, ensuring robust access controls, encryption, and network segmentation.
• Develop scripts and automation (Python, Bash) to implement security controls, monitor model integrity, and integrate vulnerability scanning and anomaly detection into AI workflows.
• Conduct deep technical threat modeling and risk assessments focused on adversarial ML, data leakage, model manipulation, and supply chain vulnerabilities.
• Support secure MLOPs development by building and maintaining secure MLOps frameworks (e.g., with Kubeflow, MLflow, or SageMaker) that support model reproducibility, traceability, and secure deployment.
• Assist in securely implementing AI systems that comply with biotech and healthcare regulations including HIPAA, GDPR, 21 CFR Part 11, and GxP.
• Develop and maintain security tooling and automation scripts to enhance visibility, vulnerability management, and model monitoring.
• Perform security assessments and harden AI platforms, APIs, data repositories, and model endpoints.
• Support engineering and implementation of tools for model explainability, bias detection, and auditability to meet regulatory and ethical AI requirements.
• Help secure infrastructure and AI workloads in cloud platforms (AWS SageMaker, Terraform, Hashicorp, etc..) by managing IAM, encryption, and monitoring controls.
• Partner with data science, R&D, and bioinformatics teams to ensure security is integrated into every stage of the AI lifecycle.
• Participate in incident response efforts involving AI models or data pipelines, conducting root cause analysis and implementing remediation.
• Continuously research emerging threats, tools, and best practices in AI security—particularly those relevant to biotech applications.

Basic Qualifications

Bachelor's degree and 2 years of Information Security or Information Technology experience

Or

Associate's degree and 3 years of Information Security or Information Technology experience

Or

High school diploma / GED and 4 years of Information Security or Information Technology experience

Preferred Qualifications

• 3-5+ years of experience designing, developing, or managing machine learning systems, with a strong understanding of AI pipelines.
• Experience with secure MLOps and MLOPS lifecycle security tools (e.g., MLflow, Kubeflow, Whylabs)
• Strong understanding of common software and web application security vulnerabilities. including OWASP top 10, SANS/CWE Top 25 etc
• Hands-on experience implementing security for AI/ML systems used in clinical research, genomics, drug discovery, diagnostics, or digital health.
• Demonstrated knowledge of adversarial machine learning techniques and defenses, including model evasion, poisoning, or inversion.
• Understanding of HIPAA, 21 CFR Part 11, GxP, GDPR, and other regulations impacting AI use in healthcare and biotechnology.
• Ability to incorporate threat intelligence into AI risk assessments and apply it to proactive model defensive engineering.

THRIVE

What you can expect of us

• Vast opportunities to learn, develop, and move up and across our global organization.
• Diverse and inclusive community of belonging, where colleagues are empowered to bring ideas to the table, take risks, and act.
• Generous Amgen Total Rewards Plan comprising healthcare, finance, wealth and career benefits.
• Flexible work arrangements.

APPLY NOW

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

careers.amgen.com

EQUAL OPPORTUNITY STATEMENT

Amgen is an Equal Opportunity employer and will consider you without regard to your race, colour, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

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