Posting Number PG191487PD
Position Number 00107291
Position Type Post Doc
FLSA Exempt
Department ID 194001 - Department of Molecular Biomedical Sciences
Department 194001 - Department of Molecular Biomedical Sciences
Job City & State Raleigh, NC
Essential Job Duties
Dr. Piedrahita’s laboratory is primarily interested in the behavior of stem and progenitor cells in vitro and in vivo, and the development of large animal models of use in human and veterinary regenerative medicine. Towards this end, his research combines techniques in functional genomics, stem cells, cell biology, embryo manipulation, and molecular biology. The primary purpose of this position is to assist in analyzing a new gene edited pig to study the role of LGR5 cells in multiple organs in particular the lung. Both during development and their involvement in diseases such as IPF, COPD and asthma. The candidate should have a strong background in cell biology, organoid biology, molecular biology and be interested in lung physiology/biology.
Duties and Responsibilities
Assist and lead projects related to the continued improvement of the LGR5 pig model. Lead the analysis of LGR5 stem cells and help elucidate their role in lung development and in repair after injury. Assist in the analysis of single cell RNAseq data to understand the developmental origin of lung LGR5 cells. Utilize organoid and indued pluripotent stem (IPS) cells models to unravel the function of LGR5 cells in the lung. Participate on other laboratory projects as needed.
Additional Duties
Other Work/Responsibilities
Participate in mentoring of other graduate and undergraduate students.
Work Schedule 8am-5pm, 5 days a week. Occasional weekends and nights
Department Required Skills
Cell biology, molecular biology, cell culture.
Preferred Years Experience, Skills, Training, Education
Organoid biology, stem cell biology including generation of IPS cell lines, lung physiology, gene expression analysis (RNAseq and scRNA seq).
Ability or interest in working with swine as a model system.
Required License or Certification
N/A
Valid NC Driver's License required? No
Commercial Driver's License Required? No
Anticipated Hiring Range $62,000
If you anticipate multiple hires from this search, please indicate how many
Job Open Date 06/06/2025
Quick Link https://jobs.ncsu.edu/postings/219545
EEO
NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity.
If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu.
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.
NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.
Read Full Description