Stanford

The Division of Immunology and Rheumatology is dedicated to institutional and community commitment to the development of research programs at Stanford that focus on clinical immunology. The Division of Immunology and Rheumatology has a longstanding tradition of excellence in patient care and is among the leading groups in the School of Medicine in cutting edge bench research, clinical trial investigation and outcomes assessment research.

The Good Lab at the Stanford University School of Medicine is seeking a talented and motivated Life Science Research Professional 1 to advance T cell immunotherapies for cancer and autoimmune diseases leveraging cutting-edge cell engineering technologies. As part of a multidisciplinary group, you will design and construct DNA sequences for cellular engineering experiments, isolate and culture primary human immune cells, and perform functional analysis of engineered cells via flow cytometry and co-culture assays. 

Additional major responsibilities will include assessing engineered T cells and other immunotherapies in mouse models of cancer and autoimmune diseases using bioluminescence imaging, peripheral blood and lymphoid organ analysis by flow cytometry, and disease scoring. A successful candidate will have a degree in immunology or related field. Previous laboratory experience in T cell engineering and mouse models of cancer and/or autoimmune diseases is highly desired, including I.V. and I.P. injections, blood, lymph node, spleen, and bone marrow isolation and analysis, and disease assessment. Additional experience with cloning, viral vector design and production, T cell cytotoxicity and suppression assays, ELISA, and high-parameter flow cytometry is highly desirable. This position represents an excellent opportunity to gain exposure to advanced genome engineering technologies in a dynamic research environment with an opportunity to impact patient outcomes.

This is a one year fixed-term position.

Duties include:

• Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
• Independently conduct experiments; maintain detailed records of experiments and outcomes.
• Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
• Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
• Assist with orientation and training of new staff or students on lab procedures or techniques.

DESIRED QUALIFICATIONS:

• Experience with mouse models of cancer or autoimmune diseases. 
• Experience in CAR T cell or immunotherapy research is a plus.
• Trained in T cell transduction, production of viral supernatants, cloning of retroviral constructs, ELISA, flow cytometry, CRISPR/Cas9, cell culture, and mouse work. 
• Experience transducing T cells is highly desired. 
• Bachelor’s degree in cell biology or molecular biology is preferred.

EDUCATION & EXPERIENCE (REQUIRED):

• Bachelor's degree in related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
• Ability to maintain detailed records of experiments and outcomes.
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Ability to work under deadlines with general guidance.
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

CERTIFICATIONS & LICENSES:

• None

PHYSICAL REQUIREMENTS*:

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
• Must have correctible vision to perform duties of the job.
• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
• Ability to work in a dusty, dirty, and odorous environment.
• Position may require repetitive motion.

WORKING CONDITIONS:

• May require working in close proximity to blood borne pathogens.
• May require work in an environment where animals are used for teaching and research.
• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
• Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
• May require extended or unusual work hours based on research requirements and business needs.

WORKING STANDARDS:

• Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
• Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned.
• Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide, http://adminguide.stanford.edu/.

The expected pay range for this position is $31.40 to $38.89 per hour.

Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.

At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.

Why Stanford is for You

Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with:

• Freedom to grow. We offer career development programs, tuition reimbursement, or audit a course. Join a TedTalk, film screening, or listen to a renowned author or global leader speak.
• A caring culture. We provide superb retirement plans, generous time-off, and family care resources.
• A healthier you. Climb our rock wall or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.
• Discovery and fun. Stroll through historic sculptures, trails, and museums.
• Enviable resources. Enjoy free commuter programs, ridesharing incentives, discounts and more.

Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources by submitting a contact form.

Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

Additional Information

• Schedule: Full-time
• Job Code: 4943
• Employee Status: Fixed-Term
• Grade: E
• Requisition ID: 106134
• Work Arrangement : On Site