Cell Culture Development Co-op

Regeneron

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.


These co-op positions are in Cell Culture Development within Preclinical Manufacturing and Process Development in Tarrytown, NY.

Project 1: This position is for Spring AND Summer (full time, about 7 months from January to August 2018)

This student will assist in the development of processes producing potential therapeutics using mammalian cell culture. He/she will use shake flasks and bench scale bioreactors to evaluate the impact of cell culture medium development feeds to improve our processes based on process parameters as well as cell metabolism data. He/she may also evaluate data using Metabolic Flux Analysis (MFA) and innovative technologies for use in cell culture medium development to improve process efficiency. Concepts from coursework in metabolism, mass transfer and biotechnology will be routinely applied to experimental and data analysis activities. The ability to design experiments, interpret results, and communicate findings will be developed as part of the cooperative education experience.


Project 2: Two positions (1) Spring AND Summer, full time, about 7 months from January to August 2018, and (2) Summer AND Fall, full time, about 7 months from about May to December 2018

The student will assist on-going work in Medium Development, within the Cell Culture Development group. Specifically, the project will focus on small-scale, high-throughput screening experiments designed to understand the metabolic profile of our cell lines. Further, the information gained from scale-down experiments will be used to tailor feeding strategies for current and future cell lines to improve productivity and product quality of continuous processes. The student will develop skills in experimental design, medium development, sterile cell culture technique and data analysis.


Project 3: This position is for Spring AND Summer (full time, about 7 months from January to August 2018)

The student will support development of late stage cell culture bioreactor processes. Project will be timeline dependent but potentially could include cell line screening and medium development for a post commercial process. This may involve evaluating compatibility of continuous technologies. Daily responsibilities will include:
-Cell cultivation in shaker flasks and bioreactors (2-5L scale)
-Benchtop bioreactor operation and maintenance
-Medium and reagent preparation
-Laboratory organization and cleaning"


Project 4: Two positions (1) Spring AND Summer, full time, about 7 months from January to August 2018, and (2) Summer AND Fall, full time, about 7 months from about May to December 2018

This student will assist in the development of processes producing potential therapeutics using mammalian cell culture. He/she will use bench scale bioreactors to evaluate cell line candidates based on cell growth, cell productivity, and product quality. Optimally performing cell lines will be transferred and utilized in clinical manufacturing of therapeutic antibodies. He/she will assist in the statistical characterization of analytical measurement variability and incorporate principles of quality by design to assess platform bioreactor setpoints used in evaluating cell line candidates. Analytical equipment characterization is vital to ensuring measurement accuracy and precision. Findings from the platform development studies, will be leveraged to increase process robustness. The student may evaluate new sensors and innovative technologies for use in cell culture development and to improve workflow efficiency and process consistency. Concepts from coursework in process control, mass transfer, and basic chemistry will be routinely applied to experimental activities. The ability to design experiments, interpret results, and communicate findings will be developed as part of the cooperative education experience.


Project 5: This position is for Summer AND Fall, full time, about 7 months from about May to December 2018

This student will assist in the development of processes producing potential therapeutics using mammalian cell culture. He/she will use sterile technique in executing shake flask and benchtop-scale bioreactor experiments to develop cell culture media formulations that improve cell growth, cell productivity, and product quality. He/she may also evaluate different technologies for their potential use in development programs. Concepts from coursework in cell biology, mass transfer, and basic chemistry will be routinely applied to experimental activities. The ability to design experiments, interpret results, and communicate findings will be developed as part of the cooperative education experience.

Start building your skills at Regeneron.
• Prefer an undergraduate student
• Must be pursuing a degree in Chemical Engineering, Bioengineering, Biomedical Engineering or similar
• Preference given to students who have taken biology, biochemistry, chemistry, bioprocessing and/or related courses
• Cell culture experience preferred

General Co-op Program Requirements:
• Must be enrolled in, or accepted to, an academic program pursuing an Associate's, Bachelor's, Master's, or PhD
• Prefer demonstrated leadership in areas such as campus activities, clubs, sports or the community
• Minimum GPA of 3.0

Other Details:
• A free shuttle is offered from the North White Plains or Tarrytown train stations to the Tarrytown campus


This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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Confirmed 14 hours ago. Posted 30+ days ago.

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