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Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Job Description

The Biologics Drug Product Development (Bio DPD) is a global organization within AbbVie that is responsible for developing and characterizing drug product formulations and manufacturing processes for biologics and small molecule injectables from early development through commercialization and life cycle management support.

AbbVie is seeking a highly motivated scientist with a proven track record in formulation and process development to serve as a Senior Scientist in the Bio DPD group in Lake County. This position will be an integral part of the product development and CMC teams and will have strong collaborations with the Pre-formulation, analytical, process development functions, the Drug Product Pilot Plants, third party manufacturers and AbbVie’s Operations S&T and Commercial Manufacturing functions.

The position can be filled at the Senior Scientist I or Senior Scientist II level depending on the candidates’ qualifications and experiences.

Key Responsibilities:

  • Lead the design and execution of experiments to define and characterize formulations for a wide range of biologics modalities (monoclonal antibodies, bispecific antibodies, antibody drug conjugates, fusion proteins, peptides, AAVs) as well as small molecule injectables.
  • Serve as a subject matter expert in biologics formulation development (liquid and lyophile).
  • Lead the design and execution of formulation robustness studies.
  • Support the design and execution of process development studies for a wide range of processes including freeze-thaw, compounding, mixing, filtration, filling, and freeze-drying.
  • Support scale-up and technology transfer activities to internal and external manufacturing sites.
  • Participate in or lead matrix drug product teams for one or more projects.
  • May represent the Bio DPD function in the cross-functional Product Presentation and Device Strategy Team (PPDST) and the CMC team.
  • Keep abreast of the latest advances in biologics and sterile products formulation development and lyophilization.
  • Initiate and/or support scientific initiatives to drive innovation, continuously enhance capabilities and improve business processes.
  • Effectively and timely communicates study plans, risks and mitigation plans to stakeholder and line management.

Qualifications

Basic Qualifications:

  • For Senior Scientist II, Bachelors, Masters, or PhD in pharmaceutics, pharmaceutical sciences, chemistry, chemical engineering, or related disciplines with 11+ (Bachelors), 9+ (Masters), or 3+ (PhD) years of relevant industry experience.
  • For Senior Scientist I, Bachelors, Masters, or PhD in pharmaceutics, pharmaceutical sciences, chemistry, chemical engineering, or related disciplines with 8+ (Bachelors), 6+ (Masters), or 0+ (PhD) years of relevant industry experience.
  • Proven ability to solve critical scientific problems.
  • Hands-on experience with biologics formulation development and lyophilization.
  • Hands-on experience with analytical and biophysical characterization of proteins, and solid-state characterization methods.
  • Solid understanding of biologics degradation mechanisms and stabilization strategies.
  • Hands-on experience with Design of Experiments (DoE), multivariate statistical analyses and data visualization tools.
  • Experience with formulation development for drying technologies such as spray drying and spray freeze-drying is a plus.

Key Competencies:

  • Deep scientific knowledge and significant hands-on experience in biologics formulation.
  • Effectively communicates to influence others, drives technical excellence, and inspires continuous improvement.
  • Builds strong relationships with peers and cross-functional partners to enable higher performance.
  • Connects ideas from disparate fields, integrates data and information quickly, and takes risks to achieve the highest performance.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our short-term incentive programs.
  • This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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Confirmed 6 hours ago. Posted 2 days ago.

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