The mission of the department of Cell, Developmental and Cancer Biology at OHSU is to improve our basic understanding of biological mechanisms relevant to human health and disease. The department is composed of 25 faculty with research spanning mechanisms of cellular crosstalk, epigenetic regulation, cell signaling, and immune activation across cancer, infection, and other disease pathologies.
A Senior Research Associate position focused on cancer immunology is available in the lab of Dr. Megan Burger at the OHSU Knight Cancer Institute. We seek an enthusiastic and dedicated Ph.D. scientist with experience in immunology and/or cancer biology and mouse models to join our team.
The Burger Lab is focused on uncovering factors regulating T cell responses against cancer to inform the design of next generation cancer immunotherapies. We seek a Senior Research Associate to lead projects focused on 1) antigen-driven dynamics of the anti-tumor T cell response or 2) tumor microenvironment regulation of T cell responses to lung cancer. Mechanistic findings will be translated to the design and preclinical testing of cancer immunotherapies. More information on our research and relevant publications can be found at our website: https://www.ohsu.edu/school-of-medicine/burger-lab.
The Senior Research Associate will work collaboratively with Dr. Burger to develop research directions and will independently and collaboratively drive project aims. Projects will utilize genetically engineered mouse models of lung cancer paired with single-cell analysis platforms, including high dimensionality flow cytometry, single-cell RNA-sequencing, and spatial profiling to deeply investigate tumor-immune crosstalk. The Senior Research Associate will also be responsible for establishing standard operating procedures in the lab and overseeing junior research staff.
Specific technical duties will include:
Additional duties will include:
To apply online, upload a CV/resume, cover letter and the names and contact information for three references.
WORKING CONDITIONS:
Work is generally 40 hours per week during normal working hours, however, some evening and weekend work may be necessary. Additional safety training will be required to work with cell lines/ infectious bacteria or viruses/ working with in a BSL-2 environment. Working with laboratory animals is required, as well as with human blood samples.
PHYSICAL DEMANDS & EQUIPMENT USAGE:
Personnel will need to work at lab benches or desks for up to 8 hours at a time. Ability to perform repetitive lab manipulations (gripping, grasping, reaching, twisting), move lab equipment under 25 lbs with accommodation. Personal protective equipment must be worn as required. (Gloves, eyewear, lab coat, etc).
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.
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