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Department 00276 - Pharmacology and Toxicology Job Summary

The successful applicants will join a vibrant team of researchers committed to understanding the biology of pathological aggression and tic disorders. Our research is based on a translational strategy, which combines clinical and preclinical research with a strong focus on the development of novel therapies for these disorders. To this end, we have developed unique models of these conditions, and have already successfully translated some of our discoveries into clinical trials. Our multifaceted approach integrates behavioral, biochemical, molecular biological, and neuroanatomical techniques, and offers an exciting opportunity to work on cutting-edge research and make a tangible impact in these critical areas of medical science. Our laboratory collaborates with a vast network of biologists and clinicians all over the world and is currently spearheading clinical and preclinical research to solve some of the major questions related to these disorders, including the mechanisms of sex differences, as well as the neural processes whereby stress exacerbates symptoms.

Candidates should hold a Ph.D. in Pharmacology, Neuroscience, Molecular Biology, Neuroendocrinology, or related fields with an established track record in one or more of the following:

1. Protein analyses.

2. Immunofluorescence.

3. Behavioral procedures – rodents, preferably previous experience with operant chambers.

Experience with animal models is essential.

Proven experience in working with research animals (mice and rats) required. Knowledge of behavioral paradigms and tests, complex laboratory techniques, equipment, terminology, materials, and substances.

Proven experience in biochemical analyses such as western blot, immunofluorescence, immunohistochemistry, PCR and qPCR, ELISA required.

Skills in the use of laboratory equipment, stereotaxical manipulation, ability to create and analyze statistical calculations and prepare reports and manuscripts required.

Demonstrated human relations, coordination and supervision of laboratory activities, laboratory management, and effective communication skills also required.

Previous experience in optogenetic, neuroanatomical tract-tracing, operant conditioning chamber, and self-administration are preferred.

  • Ph.D. in the field of Neuroscience, Pharmacology, Pharmacotherapy, Toxicology.
  • Proven experience in working with research animals and in biochemical analyses.
  • Knowledge of steroids, neuroactive steroids, brain neurotransmitters (serotonin, dopamine).
  • Fluency in English (written and oral).

Responsibilities

  • Senior laboratory personnel conducting behavioral, neurosurgical, and neurochemical research.
  • Generates and characterizes animal models of pathological aggression.
  • Organizes and conducts behavioral experiments.
  • Conducts literature reviews to obtain abstracts and information to be utilized in research.
  • Makes statistical calculations, analyzes data, prepares reports summarizing results, prepares manuscripts and grants.
  • Supervises the care of research animals; collects animal tissues (brain areas) and specimen for laboratory analyses.
  • Supervises and coordinates the activity of laboratory technicians assigned to his project, and research scholars.
  • Purchases laboratory supplies, materials, and research animals.
  • Collaborates with the Principal Investigator and the Research Scientist in laboratory management, setting up of new methods and assays to accomplish scientific objectives, preparation of IACUC and EHS/OEHS protocols, University and Companies contracts, preparation of reports, manuscripts, grants.

Problem solving: This position will assist the Principal Investigator in planning and designing new methods and techniques. Work will require exercising independent judgement and theoretical knowledge of steroids, neuroactive steroids, and neurotransmitters biochemistry. This position will include supervision of laboratory personnel and coordination of their activities. Work will be carried out in accordance with periodic conferences with the Principal Investigator.

Comments. Work environment and level of frequency that may be required:

Nearly continuously: Laboratory, animal facilities and office environment.

Often: Infectious disease, oils (air or skin exposure), hazards (exposure to chemicals).

Physical requirements and level of frequency that may be required:

Nearly continuously: Hearing, listening, talking.

Often: Repetitive hand motion (typing), walking, standing, sitting.

Minimum Qualifications Preferences Additional Information

The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with prior URS service, may elect to enroll in URS if they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at (801) 581-7447 for information. Individuals who previously retired and are receiving monthly retirement benefits from URS are subject to URS’ post-retirement rules and restrictions. Please contact Utah Retirement Systems at (801) 366-7770 or (800) 695-4877 or University Human Resource Management at (801) 581-7447 if you have questions regarding the post-retirement rules.

This position may require the successful completion of a criminal background check and/or drug screen.

The University of Utah values candidates who have experience working in settings with students and patients from all backgrounds and possess a strong commitment to improving access to higher education and quality healthcare for historically underrepresented students and patients.

All qualified individuals are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law. Upon request, reasonable accommodations in the application process will be provided to individuals with disabilities.

The University of Utah is an Affirmative Action/Equal Opportunity employer and does not discriminate based upon race, ethnicity, color, religion, national origin, age, disability, sex, sexual orientation, gender, gender identity, gender expression, pregnancy, pregnancy-related conditions, genetic information, or protected veteran’s status. The University does not discriminate on the basis of sex in the education program or activity that it operates, as required by Title IX and 34 CFR part 106. The requirement not to discriminate in education programs or activities extends to admission and employment. Inquiries about the application of Title IX and its regulations may be referred to the Title IX Coordinator, to the Department of Education, Office for Civil Rights, or both.

To request a reasonable accommodation for a disability or if you or someone you know has experienced discrimination or sexual misconduct including sexual harassment, you may contact the Director/Title IX Coordinator in the Office of Equal Opportunity and Affirmative Action (OEO/AA). More information, including the Director/Title IX Coordinator’s office address, electronic mail address, and telephone number can be located at: https://www.utah.edu/nondiscrimination/

Online reports may be submitted at oeo.utah.edu

https://safety.utah.edu/safetyreport This report includes statistics about criminal offenses, hate crimes, arrests and referrals for disciplinary action, and Violence Against Women Act offenses. They also provide information about safety and security-related services offered by the University of Utah. A paper copy can be obtained by request at the Department of Public Safety located at 1658 East 500 South.

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Confirmed 22 hours ago. Posted 30+ days ago.

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