North Atlantic Treaty Organization (NATO) has flagged the Senior Scientist job as unavailable. Let’s keep looking.

Make your mark for patients

We are looking for a Gene Therapy Downstream Process Sciences Senior Scientist who’s dynamic, resilient and flexible to join us in our Gene Therapy Process Development team, in Belgium

About the role

The Gene Therapy (GT) Downstream Process Sciences Senior Scientist will be responsible for supporting Downstream Process Development activities for UCB’s recombinant adeno-associated virus (rAAV) gene therapy products. This individual will be accountable for design and management of process development, characterization, and tech transfer of rAAV purification processes.

The Senior Scientist will collaborate with internal and external laboratories to support development of downstream processes and definition of an AAV production platforms and manufacturing facility requirements for UCB’s gene therapy offerings.

This role will start at a temporary site based in Leuven to support laboratory activities and will travel periodically to UCB site based in Braine-l’Alleud for department meetings. This individual will function remotely during the design and build of the new gene therapy laboratories then will move onsite to support start-up and operation of the development labs when the facility is online at Braine l’Alleud. The candidate may also travel (10%) to directly support operations at other sites.

What you’ll do:

  • Act as a downstream process development technical subject matter expert for rAAV gene therapy products supporting facility design, Quality-by-Design (QbD) process development, and pre-clinical and clinical manufacturing.
  • Collaborate and present to cross-functional internal and external CMC technical teams.
  • Design and execute chromatography and filtration studies for development of processes supporting First in Human studies through commercialization for rAAV gene therapy products.
  • Author & review technical documents including CMC regulatory sections, process descriptions, study designs, SOPs, technical position papers, & technical reports.
  • Identify, evaluate, and implement new technologies to improve and refine rAAV purification platforms.

Interested? For this role we’re looking for the following education, experience and skills

  • PhD or master’s degree in chemical engineering, bio engineering, biochemistry, virology or related disciplines.
  • At least 6 to 8 years of industrial experience in Process Development of large molecules or cellular therapies.
  • Excellent technical knowledge of biologics downstream manufacturing and process development (chromatography, TFF, NFF). Experience with rAAV manufacturing is desired.
  • Knowledge of cGMP manufacturing guidance and experience with technical investigations and root cause analysis.
  • Experience in Technical Project Leadership.
  • Experience with data and statistical analysis.
  • Very good command in English, both spoken and written.


Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

About us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

Why work for us?

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

Learn more about sustainability at UCB and how it is integrated into our business approach.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/colour/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

Read Full Description
Confirmed 13 hours ago. Posted 30+ days ago.

Discover Similar Jobs

Suggested Articles