The Broad Institute stands on the leading edge of biomedical research, with a mission to broadly disseminate discoveries and information to the scientific community to propel the understanding and treatment of disease. Towards this goal, the Broad Institute partners with both academic and industrial scientists to develop novel therapeutics. These partnerships often include cutting-edge projects not typically pursued by traditional pharmaceutical companies.
The Cardiovascular Disease Initiative (CVDi) at the Broad Institute of Harvard and MIT aims to exploit the novel technologies developed and utilized at the Broad to advance our understanding of disease mechanisms, identify potential biomarkers, and ignite needed progress in therapeutics. To accelerate this initiative, CVDi is looking for an exceptional candidate to lead its new Precision Cardiology Laboratory. This laboratory will operate as a cross-functional scientific team engaged in multidisciplinary research within a strategic industry partnership, aimed at high-resolution mapping of cardiovascular tissue in the context of heart failure. The successful candidate will take a lead role in defining the scientific vision of the Precision Cardiology Laboratory and directing the development and implementation of research plans and organizational structures that ensure achievement of Program and Institute goals.
Defines and translates the vision of the Precision Cardiology Laboratory into collaborative research plans, and drives strategic planning process with industry partner to ensure that goals are aligned with the vision of the organization.
Functions as a key resource for the development and comprehensive understanding of the Program’s current scientific goals and obligations to funding sources.
Works with Broad’s Program and Platform leaders and project management staff to ensure project execution.
Works with the leadership team to review project budgets and resources to ensure they are in line with objectives. Assists in evaluating space and staffing needs, follows through with relevant administrative departments.
Directs laboratory staff to maximize the productivity of the scientists by establishing and transmitting clear goals and priorities, structuring groups according to meet scientific needs, and suggesting allocation of resources appropriately.
Monitors progress on the overall portfolio of projects, and prepares status reports as necessary. Documents and communicates requirements to outside collaborators and group leaders. Communicates status of development projects, deadlines, and challenges between groups at Broad and the industry partner.
Participates in scientific meetings and seminars and represents CVDi at internal and external meetings and conferences. Assists Communications Group on publications, press and other media releases.
Supervises and mentors cross-disciplinary scientific staff, through goal setting, career development discussions, and written performance reviews. Will provide major input to staffing of project teams and hire additional staff as required.
Performs other related responsibilities as necessitated by the position.
Ph.D. and/or M.D. in biomedical research (molecular, chemical biology, cell biology, or a related field), with post-doctoral training and/or demonstrated scientific contributions to the field
Minimum of 10 years of experience in an industry or academic research environment, including significant experience managing labs and/or research projects, ideally in a high-throughput, collaborative research environment.
Experience with cellular and/or animal modeling of cardiovascular disease biology preferred.
Lab will draw upon techniques ranging from stem cell models of disease, single cell RNA seq, advanced imaging techniques, genome editing methods, proteomics, epigenomics to genetics.
Excellent management skills including the ability to: set high, but attainable, goals; define priorities and timelines; manage individual performance; and infuse the team with a sense of purpose and urgency.
Outstanding record of technical proficiency, scientific creativity, effective collaboration.
Demonstrated success in managing complex, large, multidisciplinary projects, with experience across a broad range of research areas such as general cardiovascular physiology, genomics, epigenomics, proteomics, assay development, and phenotypic screening.
Demonstrated strength in building excellent working relationships, initiating new collaborations and an enthusiasm for taking a hands-on approach to collaborative scientific discovery efforts.
Must enjoy working in a fast paced, cutting-edge and challenging environment.
Ability and willingness to think “outside the box” to develop and adopt relevant emerging technologies
Excellent written and oral communication skills with a strong record of research publications and high profile scientific presentations.
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